Plugin
Additional alignment plugin
This extension allows for use of two other alignment methods which are otherwise not distributed with CLC Workbench.
Alignment methods
Two different alignment methods are included in this extension: ClustalW and Muscle. For more detailed information on each of the alignment methods we encourage you to read the original research papers and the respective websites of the different methods. A recent paper describes some of the below mentioned algorithms and their strengths [Edgar and Batzoglou, 2006].
| Method | Website | Publication | Platform |
|---|---|---|---|
| ClustalW | More information | Thomsen et al., 1994 | Cross-platform |
| Muscle | More information | Edgar, 2004b; Edgar, 2004a | Cross-platform |
When the plug-in is installed, you will see the new alignment methods in the Toolbox under Alignments and Trees -> External Alignment. When you run the alignments, there are a number of parameters that can be set. You can also specify command line instructions.

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