Structural variations are a common event in all species (~12% of the human genome include structural variations) and they play an important part in the evolution of species as well as the development of human diseases like cancer and Autism Spectrum Disorder. The Structural Variation Plug-in tool is designed to identify structural variants such as insertions, deletions, inversions, translocations and tandem duplications in read mappings. It relies exclusively on information derived from unaligned ends (also called 'soft clippings') of the reads in the mappings.

You can download and install the plugin file for the Workbench. If you wish to install the plugin on your CLC Server, please download the plugin file and install it using the web administration interface.