Secondary Protein Structure Prediction
You can predict Alpha-helices and Beta-sheets (strands) based on Hidden Markov Model (HMM) algorithms. The HMMs are trained on a large number of high quality data from the PDB database, which is an archive of experimentally-determined, biological macromolecule 3-D structures from the Brookhaven National Laboratory.Performing secondary structure predictions in the workbench is done by simply selecting one or more protein sequences in the file manager, and thereafter choosing to predict secondary structures on the selected sequences.
Each predicted secondary structure annotation will carry a tooltip note saying that the corresponding annotation is predicted with CLC Protein Workbench. Additional notes can be added through the Add Annotation feature of the workbench.
These annotations, as well as all other annotations related to the sequence(s), can be selected individually for viewing by the user.
Click here to read more about sequence viewing
Annotated sequences can be saved for later use and re-editing.























