Antigenicity

• [Welling et al., 1985] Welling et al. used information on the relative occurrence of amino acids in antigenic regions to make a scale which is useful for prediction of antigenic regions. This method is better than the Hopp-Woods scale of hydrophobicity which is also used to identify antigenic regions.
  
• A semi-empirical method for prediction of antigenic regions has been developed [Kolaskar and Tongaonkar, 1990]. This method also includes information of surface accessibility and flexibility and at the time of publication the method was able to predict antigenic determinants with an accuracy of 75%.

Antigenicity of sequences are displayed as antigenicity plots, which may include plots for one or more sequences at the same time, and for alignments.

The workbench includes many options of adjusting the layout of the graphs. Some of these view preferences are

• Dot type
• Dot color
• Line width
• Line type
• Line color