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Advanced contig assembly
In CLC DNA Workbench and CLC Main Workbench, DNA sequence reads can be imported, trimmed and assembled from automated sequencing machines. A number of different file formats such as e.g. .SCF, .ABI, and PHD files are supported.
Some of the many advantages of CLC bio’s contig assembly framework are:
- Customized graphical display of trace data and quality scores
- Automatic annotation of reference sequences with known SNP's from the dbSNP database
- An integrated framework allows the use of sequence annotation (such as SNP information) to guide the interpretation of assembly results
- State-of-the-art assembly algorithms
- Automatic trimming of sequence reads based on quality scores, ambiguity characters and vector contamination
- Quick-keys for lightning fast manual inspection and editing of contigs
- Graphical illustration of read coverage for an easy overview of contig confidence
Click below to read more about Advanced Contig Assembly:
- Importing and viewing trace data
- Trimming of sequences
- Assemble without use of reference sequence
- Assemble to reference sequence
- View and edit contigs
Interested in assembly of 454, Illumina Genome Analyzer, or SOLiD data?
- Click here to get an overview of CLC Genomics Workbench
