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System requirements

System requirements

Desktop software

CLC Genomics Workbench

  • Windows Vista, Windows 7, Windows 8 or Windows Server 2008
  • Mac OS X 10.7 or later.
  • Linux: RHEL 5.0 or later. SUSE 10.2 or later. Fedora 6 or later.
  • 2 GB RAM required
  • 4 GB RAM recommended
  • 1024 x 768 display required
  • 1600 x 1200 display recommended
  • Intel or AMD CPU required

    Special requirements for the 3D Molecule Viewer System requirements

      • A graphics card capable of supporting OpenGL 2.0.
      • Updated graphics drivers. Please make sure the latest driver for the graphics card is installed.

      System Recommendations

      • A discrete graphics card from either Nvidia or AMD/ATI. Modern integrated graphics cards (such as the Intel HD Graphics series) may also be used, but these are usually slower than the discrete cards.
      • A 64-bit workbench version is recommended for working with large complexes.

  • Special requirements for read mapping. The numbers below give minimum and recommended memory for systems running mapping and analysis tasks. The requirements suggested are based on the genome size. Systems with less memory than specified below will benefit from installing the legacy read mapper plugin (see http://www.clcbio.com/plugins). This is slower than the standard mapper but adjusts to the amount of memory available.
    • E. coli K12 ( 4.6 megabases)
      • Minimum: 2 GB RAM
      • Recommended: 4 GB RAM
    • C. elegans ( 100 megabases) and Arabidopsis thaliana ( 120 megabases)
      • Minimum: 4 GB RAM
      • Recommended: 8 GB RAM
    • Zebrafish ( 1.5 gigabases)
      • Minimum: 8 GB RAM
      • Recommended: 16 GB RAM
    • Human ( 3.2 gigabases) and Mouse ( 2.7 gigabases)
      • Minimum: 24 GB RAM
      • Recommended: 48 GB RAM

  • Special requirements for de novo assembly. De novo assembly may need more memory than stated above – this depends both on the number of reads, error profile and the complexity and size of the genome. See http://www.clcbio.com/white-paper for examples of the memory usage of various data sets.
  • 64 bit computer and operating system required to use more than 2 GB RAM

CLC Cancer Research Workbench

  • Windows Vista, Windows 7, Windows 8 or Windows Server 2008
  • Mac OS X 10.7 or later.
  • Linux: Red Hat 5.0 or later. SUSE 10.2 or later. Fedora 6 or later.
  • 2 GB RAM required
  • 4 GB RAM recommended
  • 1024 x 768 display required
  • 1600 x 1200 display recommended
  • Intel or AMD CPU required
  • Minimum 10 GB free disc space in the tmp directory
  • Minimum 80 GB free disc space required in the CLC_References directory (if you are not connected to a server). If you have less free disc space available it is possible to change the reference data location. How to do this is described in Download and configure reference data

  • Special requirements for read mapping. The numbers below give minimum and recommended memory for systems running mapping and analysis tasks. The requirements suggested are based on the genome size. Systems with less memory than specified below will benefit from installing the legacy read mapper plugin (see http://www.clcbio.com/plugins). This is slower than the standard mapper but adjusts to the amount of memory available.
    • Human ( 3.2 gigabases) and Mouse ( 2.7 gigabases)
      • Minimum: 24 GB RAM
      • Recommended: 48 GB RAM

CLC Drug Discovery Workbench

  • Windows Vista, Windows 7, Windows 8 or Windows Server 2008
  • Mac OS X 10.7 or later.
  • Linux: RHEL 5.0 or later. SUSE 10.2 or later. Fedora 6 or later.
  • 2 GB RAM required
  • 4 GB RAM recommended
  • 1024 x 768 display required
  • 1600 x 1200 display recommended
  • Intel or AMD CPU required

3D Graphics Requirements

  • A graphics card capable of supporting OpenGL 2.0.
  • Updated graphics drivers. Please make sure the latest driver for the graphics card is installed.

3D Graphics Recommendations

  • A discrete graphics card from either Nvidia or AMD/ATI. Modern integrated graphics cards (such as the Intel HD Graphics series) may also be used, but these are usually slower than the discrete cards.
  • A 64-bit workbench version is recommended for working with large complexes.

CLC Main Workbench

  • Windows Vista, Windows 7, Windows 8 or Windows Server 2008
  • Mac OS X 10.7 or later.
  • Linux: RHEL 5.0 or later. SUSE 10.2 or later. Fedora 6 or later.
  • 32 or 64 bit
  • 1 GB RAM required
  • 2 GB RAM recommended
  • 1024 x 768 display required
  • 1600 x 1200 display recommended

Special requirements for the 3D Molecule Viewer System requirements

  • A graphics card capable of supporting OpenGL 2.0.
  • Updated graphics drivers. Please make sure the latest driver for the graphics card is installed.

System Recommendations

  • A discrete graphics card from either Nvidia or AMD/ATI. Modern integrated graphics cards (such as the Intel HD Graphics series) may also be used, but these are usually slower than the discrete cards.
  • A 64-bit workbench version is recommended for working with large complexes.

CLC Assembly Cell

  • Windows Vista, Windows 7, Windows 8 or Windows Server 2008
  • Mac OS X 10.7 or later.
  • Linux: RHEL 5.0 or later. SUSE 10.2 or later. Fedora 6 or later.
  • 1024 x 768 display recommended
  • Intel or AMD CPU required

  • Special requirements for read mapping. The numbers below give minimum and recommended memory for systems running mapping and analysis tasks. The requirements suggested are based on the genome size. Systems with less memory than specified below will benefit from installing the legacy read mapper plugin (see http://www.clcbio.com/plugins). This is slower than the standard mapper but adjusts to the amount of memory available.
    • E. coli K12 ( 4.6 megabases)
      • Minimum: 500 MB RAM
      • Recommended: 1 GB RAM
    • C. elegans ( 100 megabases) and Arabidopsis thaliana ( 120 megabases)
      • Minimum: 1 GB RAM
      • Recommended: 2 GB RAM
    • Zebrafish ( 1.5 gigabases)
      • Minimum: 5 GB RAM
      • Recommended: 8 GB RAM
    • Human ( 3.2 gigabases) and Mouse ( 2.7 gigabases)
      • Minimum: 16 GB RAM
      • Recommended: 24 GB RAM

  • Special requirements for de novo assembly. De novo assembly may need more memory than stated above – this depends both on the number of reads, error profile and the complexity and size of the genome. See http://www.clcbio.com/white-paper for examples of the memory usage of various data sets.
  • 64 bit computer and operating system required to use more than 2 GB RAM

System requirements for CLC License Server

The license server does not require much in terms of processing power and it only consumes a few megabytes of memory. This means that if you are putting together a dedicated server specifically for use as a license server, a modestly powered system equipped with a high number of redundant components will probably be a better investment than a system which is faster, has more memory, etc.

The license server is available for the following operating systems:

  • Microsoft Windows XP, Windows Vista, or Windows 7, Windows Server 2003 or Windows Server 2008
  • Mac OS X 10.5 or later
  • Red Hat Linux
  • Fedora Core Linux
  • SUSE Linux

The license server works – or can be made to work – on many other Linux distributions as well. If you are interested, please contact support@clcbio.com.

Java

The CLC Workbenches are built using Java technology. If you are a Windows, Mac OS X or Linux user, the CLC Workbench includes a JRE (Java Runtime Environment) which is needed to run the CLC Workbench. This JRE will not interfere with existing JRE’s on your computer and will only be used to run the CLC Workbench.

Mac and the Mac logo are trademarks of Apple Computer, Inc., registered in the U.S. and other countries. Microsoft, Windows and the Windows logo are either registered trademarks or trademarks of Microsoft Corporation in the United States and other countries.

Server system requirements

Enterprise solutions

Server operating system

  • Windows Vista, Windows 7, Windows 8, or Windows Server 2008.
  • Mac OS X 10.7 or later.
  • Linux: Red Hat 5 or later. SUSE 10.2 or later. Fedora 6 or later.
  • The CLC Server and its backends, including the CLC Server job nodes and the grid nodes, must run on the same type of operating system.

Server hardware requirements

  • Intel or AMD CPU required
  • Computer power: 2 cores required. 8 cores recommended.
  • Memory: 4 GB RAM required. 16 GB RAM recommended.
  • Disk space: 500 GB required. More needed if large amounts of data is analyzed.

Special memory requirements for working with genomes

A 64-bit computer and operating system is necessary if you wish to utilize more than 2 GB RAM.

The numbers below give minimum and recommended amounts for systems running mapping and analysis tasks. The requirements suggested are based on the genome size.

  • E. coli K12 ( 4.6 megabases)
    • Minimum: 2 GB RAM
    • Recommended: 4 GB RAM
  • C. elegans ( 100 megabases) and Arabidopsis thaliana ( 120 megabases)
    • Minimum: 4 GB RAM
    • Recommended: 8 GB RAM
  • Zebrafish ( 1.5 gigabases)
    • Minimum: 8 GB RAM
    • Recommended: 16 GB RAM
  • Human ( 3.2 gigabases) and Mouse ( 2.7 gigabases)
    • Minimum: 24 GB RAM
    • Recommended: 48 GB RAM

Special requirements for de novo assembly

De novo assembly may need more memory than stated above – this depends both on the number of reads and the complexity and size of the genome. See http://www.clcbio.com/white-paper for examples of the memory usage of various data sets.

Clients:

Analysis on the CLC Genomics Server can only be initiated from either CLC Genomics Workbench or the Command Line Tools, thus not from other Workbenches from CLC bio.

Scope of requirements

All the system requirements on this page are requirements for the most recent versions of the products. For requirements for older versions, please refer to the user manual for that specific version.